Mengungkap Potensi Senyawa pada Daun Jarak Pagar (Jatropha curcas L.) sebagai Antivirus Secara In Silico

Authors

  • Fika Nur Andini Putri Program Studi Pendidikan Biologi Universitas Nusantara PGRI Kediri
  • Raheva Miftakhul Janah Progam Studi Pendidikan Biologi Universitas Nusantara PGRI Kediri
  • Shafira Aurelia Rizky Azzahra Progam Studi Pendidikan Biologi Universitas Nusantara PGRI Kediri
  • Tia Hartanti Program Studi Pendidikan Biologi Universitas Nusantara PGRI Kediri
  • Agus Muji Santoso Program Studi Pendidikan Biologi Universitas Nusantara PGRI Kediri

DOI:

https://doi.org/10.29407/rxfc4h91

Keywords:

Antiviral, Jatropha curcas

Abstract

Jatropha curcas L. is a medicinal plant widely used in traditional medicine. The leaves of J. curcas contain bioactive compounds that are potential antiviral agents. This study aims to identify and analyze the potential antiviral compounds present in J. curcas leaves. A descriptive exploratory method was employed using online databases PubChem and Way2Drug. The exploratory analysis revealed several bioactive compounds with significant antiviral activity, including Phytol, Linalool, and E-Geranylacetone, which exhibited high probability of activity (PA) values. These findings indicate that J. curcas leaves possess promising potential as a natural source of antiviral agents.

References

Adinata, Khosimah,P.I, Anam, K and Kusrini, D. 2013. Identifikasi Senyawa Metabolit Sekunder Fraksi Aktif Daun Jarak Pagar (Jatropha cursas L) dan Uji Aktivitas Larvasida terhadap Larva Nyamuk Aedes aegypti. Jurnal Kimia Sains dan Aplikasi. 16(2) : 42-45.

Aktumsek, A., Zengin, G., Guler, G.O., Cakmak, Y.S., &Duran, A. (2013). Antioxidant potentials and anticholinesterase activities of methanolic and aqueous extracts of three endemic Centaurea L. species. Food Chem. Toxicol, 55, 290–296. https://doi.org/10.1016/j.fct.2013.01.018.

Boly, R., Lamkami, T., &Guissou, I. (2016). DPPH free radical scavenging activity of two extracts from agelanthus dodoneifolius (Loranthaceae) leaves. Int J Toxicol Pharmacol Research, 8(1),29-34.

Bramasto, Y. 2003. Biji Jarak, Pemanfaatan dan Kegunaanya di Masa Mendatang. Dalam klik benih.(2)01. Balai Penelitian dan Pengembangan Teknologi Pembenihan. Badan Penelitian dan Pengembangan Kehutanan.

Erma S, Martanto M, Haryono S, Jubhar C.M. 2014. Manfaat Jarak Pagar (Jatropha curcas) Sebagai Obat Tradisional. Prosiding Seminar Nasional Raja Ampat.

Gustina, Andi N.S, Karolina S. 2022. Etnobotani Tumbuhan Obat Tradisional di Suku Colol Kabupaten Manggarai Timur. Jurnal Sains dan Teknologi, Vol.5, No.2.

Hambali, E. 2006. Jarak Pagar Tanaman Penghasil Biodiesel. Penerbit Swadaya: Jakarta.

Killicgun, H., & Dehen, Altiner. (2009). In vitro Antioxidant Effect of Rosa canina in Different Antioxidant Test Systems. Pharmacognosy Research, 1(6), 417-420. https://www.phcogres.com/article/2009/1/6/nil14.

Nuria M C, Faizatun A, dan Sumantri,2009. Uji Aktifitas Antibakteri Ekstrak Etanol Daun Jarak Pagar (Jatropa curcas L) terhadap bakteri Staphylococcus aurelus ATCC 25923, Escherichia coli ATCC 25922 dan Salmonella typhi ATCC 1408. Media Grow, (5): 26-37.

Setyaningsih D, Nurmillah O Ydan Windarwati S, 2013. Kajian Aktivitas Antioksidan dan Antimikroba Ekstrak Biji, Kulit Buah, Batang dan Daun Tanaman Jarak Pagar (Jatropha Curcas L.). Web publication. http://repository.ipb.ac.id/handle/ 123456789/19639.

Sudaryanto, Herwanto, T., Putri, S. H. (2016). Aktivitas Antioksidan Pada Minyak Biji Kelor (Moringa Oleifera L.) dengan Metode Sokletasi Menggunakan Pelarut n-Heksan, Metanol dan Etanol. JurnalTeknotan,10(2), 16–21.

Surahmaida, Umarudin, Agustina W.R., Novicalia C.D. 2021. Skrining Fitokimia Senyawa Metabolit Sekunder Ekstrak Metanol Daun Jarak Pagar (Jatropha curcas) dengan GCMS. Journal of Pharmacy and Science, Vol.6 No. 1.

Tiwa,G.F., Homenta, H., dan Hutagalung, P.S.B. 2017. Uji Efektivitas Daya Hambat Getah Daun Jarak Pagar (Jatropha curcas L) Terhadap Streptococcus mutans. Jurnal Ilmiah Farmasi. 6(4) : 192-199.

Vieira, D.S., Oliveira, F.T. de, Suarez, J.A.G., Silva, D.P. da, Bernardo, T.H.L.,&Bastos, M.L. de A. (2021). Biological activities: anti-infectious, Antioxidant and healing of the vegetable species Jatropha multifida. Rev. Bras. Enferm,74(2). e20200451 https://doi.org/10.1590/0034-7167-2020- 0451.

Yulianto, S., and Sumarmi. 2018. Aktivitas Antibakteri Ekstrak Daun Jarak Pagar (Jatropha curcas L) Terhadap Staphylococcus aureus Secara In vitro. Jurnal Terpadu Ilmu Kesehatan. 7(1) : 1-10.

Blundell AG, & Peart DR. 2001. Growth Strategies of a Shadetolerant Tropical Tree: the Interactive Effects of Canopy Gaps and Simulated Herbivory. Journal of Ecology, 89: 608–615.

Sakai, S., 2002. General flowering in lowland mixed dipterocarp forests of South-east Asia. Biological Journal of the Linnean Society, 75(2): 233-247.

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Published

2026-05-08

Issue

Vol. 3 No. 1 (2025): Inovasi Riset & PkM Saintek/Biologi dan Pembelajarannya untuk Mendukung Tujuan Pembangunan Berkelanjutan

Section

Articles

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How to Cite

Mengungkap Potensi Senyawa pada Daun Jarak Pagar (Jatropha curcas L.) sebagai Antivirus Secara In Silico. (2026). Prosiding Seminar Nasional Hayati, 3(1), 191-195. https://doi.org/10.29407/rxfc4h91

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